PT-141 (Bremelanotide)

Description

PT-141 (bremelanotide) is a cyclic seven-amino-acid melanocortin peptide that acts centrally, primarily on the MC4R receptor in the hypothalamus – distinguishing it mechanistically from vascular (PDE5) approaches. It is studied for how central melanocortin signaling participates in arousal-related neural circuits.

Mechanistic research describes PT-141 as activating hypothalamic MC4R signaling, with additional MC1R-linked anti-inflammatory and DNA-repair interest reported, examined in central-signaling and other preclinical models. Genefyx supplies it as a research reference compound, mass-spec verified with a certificate of analysis, and it is not intended for human or animal use.

How it works

Central MC4R activation in the hypothalamus → arousal/desire signaling; MC1R anti-inflammatory and DNA-repair links.

Research context

Sexual-arousal (clinical), hemorrhagic-shock, and immune-modulation research.

Handling

Lyophilized powder. Certificate of analysis, ≥99% purity.

Research use only. Not for animal or human consumption. Not approved or evaluated by the FDA — not a drug, supplement, or therapy. Price shown is a placeholder pending final pricing.